Bandyopadhyay Anuja, Bhattacharyya Subhasish, Banerjee Ambar
Department of Pediatrics (Medicine), Calcutta Medical College, 88, College Street, Kolkata 700 072, West Bengal, India.
Indian Pediatr. 2009 Jun;46(6):512-5. Epub 2009 Jan 1.
This pilot study was aimed at testing the feasibility of using a standardized questionnaire as a screening tool for detection of pediatric HIV at first contact. A prospective study was carried out on a cohort of 400 new patients attending the pediatric outdoor patient department in Medical College, Kolkata. After examining, the attending physician noted his clinical impression, filled the standardized questionnaire and scored each patient. ELISA test was performed. The results of the diagnostic tests were correlated with the clinical impression and the score. Taking a score of 9 as the cut-off, the sensitivity and specificity of the scoring system was 95.7% and 98.6% respectively. We conclude that this clinicoepidemiological scoring system may be used to screen children for HIV in resource-limited settings.
这项试点研究旨在测试使用标准化问卷作为首次接触时检测儿童艾滋病毒的筛查工具的可行性。对加尔各答医学院儿科门诊的400名新患者进行了一项前瞻性研究。检查后，主治医生记录其临床印象，填写标准化问卷并对每位患者进行评分。进行了酶联免疫吸附测定（ELISA）测试。诊断测试结果与临床印象和评分相关。以9分为临界值，评分系统的敏感性和特异性分别为95.7%和98.6%。我们得出结论，这种临床流行病学评分系统可用于在资源有限的环境中筛查儿童是否感染艾滋病毒。
