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四川省汉族人群和广西壮族自治区壮族人群中6个微型Y染色体短串联重复序列(miniY-STR)基因座的单倍型

Haplotypes of six miniY-STR loci in the Han population from Sichuan province and the Zhuang population in Guangxi Zhuang autonomous region.

作者信息

Zhang Danyan, Zhang Danmei, Wu Wei, Luo Haibo, Ye Yi, Feng Yue, Hou Yiping

机构信息

College of Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, PR China.

出版信息

Forensic Sci Int Genet. 2009 Mar;3(2):e49-51. doi: 10.1016/j.fsigen.2008.05.010. Epub 2008 Jul 9.

Abstract

Human Y-chromosomal short tandem repeat (miniY-STR) with short amplicon lengths is useful in forensic applications, especially in the analysis of degraded DNA samples. The present study aims to investigate the population database of six miniY-STR (DYS570, DYS556, DYS576, DYS522, DYS508, DYS540). 307 blood samples were taken from the Han population, and 253 samples were taken from the Zhuang population. The amplification product lengths detected ranged from 95 to 170 bp. A total of 395 haplotypes, 303 of them unique, were found. The haplotype diversity of the Han was 0.9980 and of the Zhuang 0.9965, indicating a high discriminating power of these six miniY-STR loci in these two populations.

摘要

具有短扩增子长度的人类Y染色体短串联重复序列(miniY-STR)在法医学应用中很有用,特别是在分析降解的DNA样本时。本研究旨在调查六个miniY-STR(DYS570、DYS556、DYS576、DYS522、DYS508、DYS540)的群体数据库。从汉族人群中采集了307份血液样本,从壮族人群中采集了253份样本。检测到的扩增产物长度范围为95至170 bp。共发现395种单倍型,其中303种是独特的。汉族的单倍型多样性为0.9980,壮族为0.9965,表明这六个miniY-STR基因座在这两个人群中具有较高的鉴别能力。

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