Bahloul Mabrouk, Ksibi Hichem, Khlaf Bouaziz Nadia, Dammak Hassan, Ben Hamida Chokri, Kallel Hatem, Chelly Hédi, Bouaziz Mounir
Service de Réanimation médicale CHU Habib Bourguiba Route el Ain Km 1 3029.
Tunis Med. 2008 Jun;86(6):525-8.
Acute fatty liver of pregnancy (AFLP) is a rare, potentially fatal complication that occurs in the third trimester or early postpartum period. It generally appears between weeks 30 and 38. Usually the APLF symptoms start one to two weeks before hospitalization with nausea, emesis, general uneasiness, jaundice, epigastric pain and other symptoms. A careful history and physical examination, in conjunction with compatible laboratory and imaging results, are often sufficient to make the diagnosis, and liver biopsy is rarely indicated. The maternal outcome has improved enormously during the last decade. Early diagnosis, pregnancy termination and handling in special care or treating complications has lead to good maternofetal results.
妊娠急性脂肪肝（AFLP）是一种罕见的、潜在致命的并发症，发生于妊娠晚期或产后早期。通常出现在孕30至38周之间。一般来说，AFLP症状在住院前一至两周开始出现，包括恶心、呕吐、全身不适、黄疸、上腹部疼痛等症状。详细的病史和体格检查，结合相符的实验室及影像学检查结果，通常足以做出诊断，很少需要进行肝活检。在过去十年中，孕产妇结局有了极大改善。早期诊断、终止妊娠以及在特殊护理下处理或治疗并发症已带来良好的母胎结局。
