Ben Taarit Ch, Kaffel D, Ben Maiz Hédi, Khedher Adel
Unité de rhumatologie, Service de Médecine A, Hôpital Charles Nicolle, Tunis.
Tunis Med. 2008 Jun;86(6):546-9.
To analyse and discuss cardiovascular manifestations of ankylosing spondylitis, evaluate the frequency and giving special attention to unusual forms.
We retrospectively reviewed the medical records of 21 cases with cardiovascular manifestations among 210 cases of ankylosing spondylitis seen over a 25 years period who met the Amor criteria.
Cardiovascular complications were found in 21 patients (10%): 5 (2.40%) had aortic insufficiency, 2 (0.95%) had mitral insufficiency, 1 had mitral valve prolapse, 1 had pericarditis, 10 (4.7%) had atrioventricular block and 6 (2.8%) had bundle branch block. Takayasu's disease was diagnosed in one case. Cardiovascular involvement was common In patients longer disease duration. Peripheral arthritis was found in 33% and its prevalence did not differ in patients with or without cardiac involvement.
Aortic insufficiency and conduction disturbances were the most common cause of cardiovascular involvement in ankylosing spondylitis. The funding of cardiovascular manifestations in 10% of our patients suggests that in this illness evidence of cardiac manifestations should be actively investigated in ankylosing spondylitis.
分析和讨论强直性脊柱炎的心血管表现，评估其发生率并特别关注不常见的形式。
我们回顾性分析了25年间符合阿穆尔（Amor）标准的210例强直性脊柱炎患者中21例有心血管表现患者的病历。
21例患者（10%）出现心血管并发症：5例（2.40%）有主动脉瓣关闭不全，2例（0.95%）有二尖瓣关闭不全，1例有二尖瓣脱垂，1例有心肌炎，10例（4.7%）有房室传导阻滞，6例（2.8%）有束支传导阻滞。1例诊断为高安氏病。心血管受累在病程较长的患者中常见。33%的患者有外周关节炎，其在有或无心脏受累的患者中患病率无差异。
主动脉瓣关闭不全和传导障碍是强直性脊柱炎心血管受累的最常见原因。我们10%的患者出现心血管表现提示在强直性脊柱炎中应积极检查有无心脏表现的证据。
