Liang Qi, Xie Ming
Zhong Xi Yi Jie He Xue Bao. 2009 Feb;7(2):101-4. doi: 10.3736/jcim20090201.
Based on traditional Chinese medicine theory and clinical experience, traditional Chinese herbal drug toxicity has its own special connotation. From the perspective of history and logic, the different comprehension of toxicity between Western medicine and traditional Chinese medicine was discussed after retracing the meaning of "drug toxicity" in traditional Chinese medicine. The authors suggest that it's not feasible to study the Chinese medicine coping mechanically and applying indiscriminately the concept and the research idea about modern drug toxicity since there is different understanding of "drug toxicity" between traditional Chinese medicine and Western medicine. Many control elements are involved in the use of traditional Chinese herbal drugs, and Chinese drug components and actions are complex as compared with Western drugs. More and more drugs with toxicity will be found due to the relativity of drug toxicity. Currently, the study of Chinese drug toxicity should pay more attention to the relation between the toxicity and Chinese drug nature, compatibility and the corresponding disease or syndrome pattern after making definition of Chinese drug toxicity and its connotation.
基于中医理论和临床经验，中药毒性有其独特的内涵。从历史和逻辑的角度，在追溯中医“药物毒性”含义后，探讨了中西医对毒性的不同理解。作者认为，由于中西医对“药物毒性”的理解不同，机械套用现代药物毒性的概念和研究思路来研究中药是不可行的。中药的使用涉及诸多控制因素，与西药相比，中药成分和作用更为复杂。由于药物毒性的相对性，将会发现越来越多有毒性的药物。目前，中药毒性研究在明确中药毒性及其内涵后，应更加关注毒性与中药药性、配伍以及相应病证之间的关系。
