Bills Nathan D, Hinrichs Steven H, Aden Tricia A, Wickert Robert S, Iwen Peter C
i(3)Bio, LLC, Omaha, NE 68022, USA.
Diagn Microbiol Infect Dis. 2009 Mar;63(3):292-5. doi: 10.1016/j.diagmicrobio.2008.12.002.
This report describes a case of Mycobacterium chimaera infection in a patient with a history of chronic obstructive pulmonary disease where the organism was identified by using molecular methods. M. chimaera was identified from fresh lung tissue and from an instrument-negative mycobacterial growth indicator tube broth culture. The utility of using sequence analysis of the internal transcribed spacer region for the rapid identification of a slow-growing nontuberculous Mycobacterium spp. where conventional culture methods were not successful was shown.
本报告描述了一例慢性阻塞性肺疾病患者感染嵌合体分枝杆菌的病例，该病原体通过分子方法得以鉴定。嵌合体分枝杆菌是从新鲜肺组织以及仪器阴性的分枝杆菌生长指示管肉汤培养物中鉴定出来的。研究显示，在传统培养方法未成功的情况下，利用转录间隔区序列分析快速鉴定生长缓慢的非结核分枝杆菌属的实用性。
