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一名医护人员身上出现伪装成肺部肿块的分枝杆菌感染。

Mycobacterium chimaera infection masquerading as a lung mass in a healthcare worker.

作者信息

Rosero Christian I, Shams Wael E

机构信息

Department of Internal Medicine, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, United States.

Department of Internal Medicine, Division of Infectious Diseases, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614, United States.

出版信息

IDCases. 2019 Mar 26;15:e00526. doi: 10.1016/j.idcr.2019.e00526. eCollection 2019.

DOI:10.1016/j.idcr.2019.e00526
PMID:30989052
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6446050/
Abstract

, a nontuberculous mycobacterium, is a member of the complex (MAC). This microorganism has recently gained significant notoriety for its association with outbreaks in patients exposed to contaminated heater -cooler devices used during open heart surgeries. We report a case of pulmonary infection in a healthcare worker who presented with cough, low grade fever and weight loss with evidence of a lung mass that was initially thought to be a tumor on CT scan imaging. The patient underwent partial left lung lobectomy and pathology revealed necrotizing granulomas with acid fast bacilli and a culture grew . The patient received combination antimycobacterial therapy according to susceptibility results for twelve months with complete resolution of his symptoms and radiographic findings. Infection Control investigation could not find a source of infection in the hospital where he worked during the last ten years. However, the patient rotated in different hospitals before coming to work at this facility and assisted in surgeries in several operating rooms where the heater-cooler devices in question were used.

摘要

非结核分枝杆菌是鸟分枝杆菌复合群(MAC)的成员。这种微生物最近因与心脏直视手术中使用的受污染加热 - 冷却设备接触的患者爆发感染而声名狼藉。我们报告一例医护人员的肺部感染病例,该患者表现为咳嗽、低热和体重减轻,CT扫描显示肺部有肿块,最初被认为是肿瘤。患者接受了左肺部分肺叶切除术,病理显示有坏死性肉芽肿伴抗酸杆菌,培养结果为[具体菌种未给出]。患者根据药敏结果接受了十二个月的联合抗分枝杆菌治疗,症状和影像学表现完全缓解。感染控制调查在他过去十年工作的医院中未发现感染源。然而,该患者在来此机构工作之前曾在不同医院轮转,并在几个使用了相关加热 - 冷却设备的手术室协助手术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a5/6446050/89b92cd78a14/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a5/6446050/11def74b4558/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a5/6446050/89b92cd78a14/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a5/6446050/11def74b4558/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/57a5/6446050/89b92cd78a14/gr2.jpg

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Clin Microbiol Infect. 2018 Nov;24(11):1164-1170. doi: 10.1016/j.cmi.2018.04.027. Epub 2018 May 25.
2
Comparison of methods available for identification of Mycobacterium chimaera.比较可用于鉴定耻垢分枝杆菌的方法。
Clin Microbiol Infect. 2018 Apr;24(4):409-413. doi: 10.1016/j.cmi.2017.07.031. Epub 2017 Aug 4.
3
Disseminated Presenting as Vertebral Osteomyelitis.
Open Forum Infect Dis. 2022 Jun 15;9(7):ofac287. doi: 10.1093/ofid/ofac287. eCollection 2022 Jul.
4
from Cardio Surgery Heating-Cooling Units and from Clinical Samples in Israel Are Genetically Unrelated.来自以色列心脏外科手术中的加热 - 冷却装置以及临床样本的(菌株)在基因上没有关联。
Pathogens. 2021 Oct 27;10(11):1392. doi: 10.3390/pathogens10111392.
5
Genomics With Regard to Epidemiological and Clinical Investigations Conducted for an Open Chest Postsurgical Infection Outbreak.关于开胸手术后感染暴发的流行病学和临床调查的基因组学
Open Forum Infect Dis. 2021 Apr 16;8(6):ofab192. doi: 10.1093/ofid/ofab192. eCollection 2021 Jun.
6
Disseminated Following Open-Heart Surgery, the Heater-Cooler Unit Worldwide Outbreak: Case Report and Minireview.心脏直视手术后加热器-冷却器装置全球传播疫情:病例报告与综述
Front Med (Lausanne). 2020 Jun 16;7:243. doi: 10.3389/fmed.2020.00243. eCollection 2020.
播散性 表现为椎体骨髓炎。
Case Rep Infect Dis. 2017;2017:9893743. doi: 10.1155/2017/9893743. Epub 2017 Apr 24.
4
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5
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6
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9
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