代谢综合征是一个离散的诊断类别还是连续统一体的终点？1999 - 2004年美国国家健康与营养检查调查中维度性的分类分析证据。
Is the metabolic syndrome a discrete diagnostic category or the end of a continuum? Taxometric evidence for dimensionality in the National Health and Nutrition Examination Survey 1999-2004.
作者信息
Ingram David G
机构信息
School of Medicine, University of Missouri-Columbia, Columbia, MO 65212, United States.
出版信息
Ann Epidemiol. 2009 Mar;19(3):143-7. doi: 10.1016/j.annepidem.2008.12.012.
PURPOSE
To determine whether the metabolic syndrome is a discrete diagnostic category or the end of a continuum.
METHODS
The study sample consisted of 3959 individuals from the National Health and Nutrition Examination Survey 1999-2004. The taxometric methods of mean above minus mean below a cut (MAMBAC) and maximum covariance (MAXCOV) were used. The primary numerical outcome was the comparative curve fit index (CCFI).
RESULTS
For men, the CCFI from MAMBAC and MAXCOV analyses were 0.290 and 0.260, respectively. Likewise, for women, the CCFI from MAMBAC and MAXCOV analyses were 0.317 and 0.311, respectively.
CONCLUSIONS
The results indicate that the metabolic syndrome is continuously distributed in nature, rather than a discrete diagnostic category.
目的
确定代谢综合征是一个离散的诊断类别还是连续统一体的终点。
方法
研究样本包括来自1999 - 2004年国家健康和营养检查调查的3959名个体。使用了均值以上减去均值以下切点（MAMBAC）和最大协方差（MAXCOV）的分类测量方法。主要数值结果是比较曲线拟合指数（CCFI）。
结果
对于男性，MAMBAC分析和MAXCOV分析的CCFI分别为0.290和0.260。同样，对于女性，MAMBAC分析和MAXCOV分析的CCFI分别为0.317和0.311。
结论
结果表明，代谢综合征本质上是连续分布的，而非一个离散的诊断类别。
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