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肺间质液运动的多孔相模型

Porous phase model of the lung interstitial fluid motion.

作者信息

Serikov V B

机构信息

Laboratory of Medical Research and Technology, Association Alpha, Leningrad, USSR.

出版信息

Microvasc Res. 1991 Jul;42(1):1-16. doi: 10.1016/0026-2862(91)90071-i.

DOI:10.1016/0026-2862(91)90071-i
PMID:1921750
Abstract

A mathematical model of nonsteady-state fluid movement in the lung interstitium during hydrodynamic loading is evaluated. The model is based on experimental results obtained in isolated perfused canine lungs. The interstitium is treated as a porous phase with an elastic framework, able to relax; all resistance to flux is in the interstitial tissue and not in the endothelium. A numerical iteration procedure was applied for the calculation of fluid transfer coefficients. The model describes space distribution of driving pressures in the interstitium.

摘要

对流体动力加载期间肺间质中非稳态流体运动的数学模型进行了评估。该模型基于在离体灌注犬肺中获得的实验结果。间质被视为具有弹性框架、能够松弛的多孔相;所有对通量的阻力都存在于间质组织中,而不存在于内皮中。应用数值迭代程序计算流体传输系数。该模型描述了间质中驱动压力的空间分布。

相似文献

1
Porous phase model of the lung interstitial fluid motion.肺间质液运动的多孔相模型
Microvasc Res. 1991 Jul;42(1):1-16. doi: 10.1016/0026-2862(91)90071-i.
2
[Transport of a fluid in the lung interstitial space. A model of porous medium with distributed parameters].[肺间质空间中流体的传输。一种具有分布参数的多孔介质模型]
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Fiziol Zh SSSR Im I M Sechenova. 1985 Sep;71(9):1124-30.
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The pulmonary interstitium in capillary exchange.参与毛细血管交换的肺间质。
Ann N Y Acad Sci. 1982;384:146-65. doi: 10.1111/j.1749-6632.1982.tb21369.x.
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[A description of the nonsteady-state phenomena of fluid transport in the lungs based on the equations of linear thermodynamic nonequilibrium].基于线性热力学非平衡方程对肺内流体传输的非稳态现象的描述
Nauchnye Doki Vyss Shkoly Biol Nauki. 1989(6):62-8.
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[Lymph flow and the vascular permeability of the lungs during spontaneous respiration and artificial pulmonary ventilation].[自主呼吸和人工肺通气时肺的淋巴液流动与血管通透性]
Anesteziol Reanimatol. 1981 May-Jun(3):28-32.
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Pulmonary interstitial and capillary pressures estimated from intra-alveolar fluid pressures.根据肺泡内液体压力估算的肺间质和毛细血管压力。
J Appl Physiol Respir Environ Exerc Physiol. 1978 Feb;44(2):267-76. doi: 10.1152/jappl.1978.44.2.267.
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Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: significance of elevated interstitial pressure.单克隆抗体及其他大分子在肿瘤中异质性分布的机制:间质压力升高的意义
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Vascular permeability and transvascular fluid and protein transport in the dog lung.
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