The University of Texas at Austin, Austin, TX 78712-0187, USA.
Behav Res Ther. 2009 Apr;47(4):294-300. doi: 10.1016/j.brat.2009.01.002. Epub 2009 Jan 17.
It has been suggested that obsessive-compulsive disorder is characterized by impaired inhibitory control. Response inhibition is a cognitive process required for one to cancel or suppress dominant but inappropriate responses. The present study examined response inhibition among non-treatment seeking individuals diagnosed with OCD and individuals with low levels of OCD symptoms using a computerized visual go/no-go task. Specifically, we sought to examine a prediction from the autogenous-reactive subtype model of obsessions (Lee, H.-J., & Kwon, S.-M. (2003). Two different types of obsession: autogenous obsessions and reactive obsessions. Behaviour Research and Therapy, 41, 11-29; Lee, H.-J., & Telch, M. J. (2008). Autogenous obsessions and reactive obsessions. In J. Abramowitz, S. Taylor, & D. McKay (Eds.), Obsessive-compulsive disorder: subtypes and spectrum conditions. New York: Elsevier., asserting that OCD individuals presenting with the autogenous subtype of obsessions will display greater difficulty in inhibitory control relative to individuals presenting with obsessions of the reactive subtype. Results showed that individuals with OCD of the autogenous subtype displayed more deficient inhibitory control on the visual go/no-go task as indexed by a longer response delay between the original stimuli set and the reversed stimuli set compared to individuals with OCD of the reactive subtype or individuals with low levels of OCD symptoms.
有人认为强迫症的特征是抑制控制受损。反应抑制是一种认知过程,要求一个人取消或抑制主导但不适当的反应。本研究使用计算机视觉 Go/No-Go 任务,检查了未接受治疗的强迫症患者和强迫症症状水平较低的个体的反应抑制。具体来说,我们试图检验强迫症的自体反应亚型模型的一个预测(Lee,H.-J.,& Kwon,S.-M.(2003)。两种不同类型的强迫观念:自体强迫观念和反应性强迫观念。行为研究与治疗,41,11-29;Lee,H.-J.,& Telch,M. J.(2008)。自体强迫观念和反应性强迫观念。在 J. Abramowitz,S. Taylor 和 D. McKay(编辑),强迫症:亚型和谱系条件。纽约:爱思唯尔。,断言表现出自体强迫观念的强迫症患者在抑制控制方面会遇到更大的困难,而表现出反应性强迫观念的强迫症患者则会遇到更大的困难。结果表明,与反应性强迫观念的强迫症患者或强迫症症状水平较低的个体相比,具有自体强迫观念的强迫症患者在视觉 Go/No-Go 任务中表现出更差的抑制控制,表现在原始刺激集和反转刺激集之间的反应延迟更长。