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Brugada综合征人群的远程植入式心脏复律除颤器监测

Remote implantable cardioverter defibrillator monitoring in a Brugada syndrome population.

作者信息

Sacher Frédéric, Probst Vincent, Bessouet Maider, Wright Matthew, Maluski Alexandre, Abbey Sélim, Bordachar Pierre, Deplagne Antoine, Ploux Sylvain, Lande Gilles, Jaïs Pierre, Hocini Mélèze, Haïssaguerre Michel, Le Marec Hervé, Clémenty Jacques

机构信息

CHU de Bordeaux, Université Bordeaux II, France.

出版信息

Europace. 2009 Apr;11(4):489-94. doi: 10.1093/europace/eup034. Epub 2009 Feb 14.

Abstract

AIMS

The diagnosis of Brugada syndrome (BS) is typically made in a young and otherwise healthy population. In patients with a high risk of sudden cardiac death (SCD), the only currently recommended therapy is an implantable cardioverter defibrillator (ICD), but these are not without complications. We investigated whether remote ICD monitoring could simplify follow-up and detect potential complications in these patients.

METHODS AND RESULTS

Thirty-five consecutive patients (26 males, 44 +/- 11 years) implanted with an ICD for BS with a remote monitoring ['Home Monitoring' (HM), Biotronik, Germany] system were prospectively enrolled in this study. They were matched for age, sex, and follow-up duration with 35 BS patients implanted with an ICD without this capability. During a mean follow-up of 33 +/- 17 months, the number of cardiology consultations was significantly lower in the HM group (3 +/- 2 vs. 7 +/- 3; P < 0.001). Inappropriate shock(s) [IS(s)] occurred in three patients (8.5%) in the HM group vs. six (17%) in the control group (P = NS). Ten patients in the HM group had a median of four alerts ('ventricular tachycardia/ventricular fibrillation detection' in all patients, 'shock' in three, 'ineffective shock' in two patients with shock on noise, 'extreme ventricular pacing impedance' in one patient due to lead failure, and 'deactivated therapy' in two patients with lead failure before replacement). In 5 of these 10 patients, prompt reprogramming of the ICD may have prevented IS(s).

CONCLUSION

Remote ICD monitoring in patients with BS decreases outpatient consultations and may help prevent ISs.

摘要

目的

Brugada综合征(BS)的诊断通常在年轻且其他方面健康的人群中进行。对于有心脏性猝死(SCD)高风险的患者,目前唯一推荐的治疗方法是植入式心律转复除颤器(ICD),但这些治疗并非没有并发症。我们研究了远程ICD监测是否可以简化这些患者的随访并检测潜在并发症。

方法与结果

本研究前瞻性纳入了35例连续植入带有远程监测系统(“家庭监测”(HM),德国百多力公司)的ICD用于治疗BS的患者(26例男性,年龄44±11岁)。将他们与35例植入不具备此功能ICD的BS患者按年龄、性别和随访时间进行匹配。在平均33±17个月的随访期间,HM组的心脏科会诊次数显著低于对照组(3±2次 vs. 7±3次;P<0.001)。HM组有3例患者(8.5%)发生不适当电击(IS),而对照组有6例(17%)(P=无统计学意义)。HM组有10例患者中位数有4次警报(所有患者均有“室性心动过速/心室颤动检测”,3例有“电击”,2例因噪音导致电击的患者有“无效电击”,1例因导线故障有“极端心室起搏阻抗”,2例在更换导线前因导线故障有“治疗停用”)。在这10例患者中的5例中,及时对ICD进行重新编程可能预防了IS。

结论

BS患者的远程ICD监测减少了门诊会诊次数,并可能有助于预防IS。

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