Kosinska M, Szwed A, Cieslik J, Gozdzik J, Cofta S
Department of Human Biological Development, Institute of Anthropology, Faculty of Biology, A. Mickiewicz University, Poznan, Poland.
J Physiol Pharmacol. 2008 Dec;59 Suppl 6:341-8.
Cystic fibrosis (CF) is the most common autosomal disorder in the Caucasian population. The main goal of the study was to assess the biological condition of adult patients with CS. Data of 90 CF patients aged 18-31 were considered. The biological condition was determined by the measurement of somatometric traits and the nutritional status. The results show a considerable physical retardation and a poor nutritional status of the studied patients. Nearly 45% of the patients showed symptoms of malnutrition, ranging from slight undernutrition to emaciation. The results, however, show a considerable variability of data among the CF patients compared with the healthy population. A significant relationship between the type of mutation and nutritional status was demonstrated.
囊性纤维化（CF）是白种人群中最常见的常染色体疾病。该研究的主要目的是评估成年囊性纤维化患者的身体状况。研究纳入了90名年龄在18至31岁之间的囊性纤维化患者的数据。通过测量身体测量特征和营养状况来确定身体状况。结果显示，所研究患者存在明显的身体发育迟缓以及营养状况不佳。近45%的患者表现出营养不良症状，从轻度营养不足到消瘦不等。然而，结果表明，与健康人群相比，囊性纤维化患者的数据存在相当大的变异性。研究证实了突变类型与营养状况之间存在显著关联。
