Mroz R M, Kordecki K, Kozlowski M D, Baniukiewicz A, Lewszuk A, Bondyra Z, Laudanski J, Dabrowski A, Chyczewska E
Department of Pneumology, Bialystok Medical University, Bialystok, Poland.
J Physiol Pharmacol. 2008 Dec;59 Suppl 6:491-7.
We investigate retrospectively the efficacy of self-expandable metallic stents (SEMS) for severe respiratory distress (SRD) in patients with central airway obstruction (CAO). Thirty three patients with CAO were treated with SEMS using fiberoptic bronchoscopy method. We found an intraluminal obstruction present in 7, extraluminal compression in 10, and combined stenosis in 16 cases. Tumor infiltration occupied more than 90% of the endoluminal diameter in 21, 70% in 9, and 50% in 3 cases. Obstruction was caused by primary cancer of lung in 23, thyroid in 5, and esophagus in 5 patients. Up to 3 stents per patient were placed. Double stenting (esophagus and trachea) was required in five patients. All patients exhibited symptomatic and arterial blood gas improvement. The mean follow-up was 65 (5 to 752) days. SEMS are useful for the treatment of SRD caused by CAO. The overall effect is related to the degree of tumor progression itself.
我们回顾性研究了自膨式金属支架（SEMS）对中央气道阻塞（CAO）患者严重呼吸窘迫（SRD）的疗效。33例CAO患者采用纤维支气管镜方法接受了SEMS治疗。我们发现管腔内阻塞7例，管腔外压迫10例，合并狭窄16例。肿瘤浸润占管腔内径90%以上21例，70% 9例，50% 3例。阻塞由肺癌原发23例、甲状腺癌5例、食管癌5例引起。每位患者最多置入3枚支架。5例患者需要双支架置入（食管和气管）。所有患者症状和动脉血气均有改善。平均随访65（5至752）天。SEMS对治疗CAO引起的SRD有用。总体效果与肿瘤进展程度本身有关。
