Lemmens Gilbert M D, Eisler Ivan, Buysse Ann, Heene Els, Demyttenaere Koen
University Psychiatric Centre K.U.Leuven, Campus Leuven, Leuven, Belgium.
Psychother Psychosom. 2009;78(2):98-105. doi: 10.1159/000201935. Epub 2009 Feb 13.
Family-based interventions have been shown to be effective in the treatment of depression, but they have seldom been studied in hospitalized depressed patients. This study assesses the value of the additional use of single-family or multi-family group therapy within this patient population.
Eighty-three patients were randomly assigned to: (1) the treatment programme as usual (n = 23), (2) treatment as usual combined with single-family therapy (n = 25) or (3) treatment as usual combined with multi-family group therapy (n = 35). Follow-up assessments were made at 3 months and 15 months.
Multi-family group and single-family therapy conditions showed significantly higher rates of treatment responders than the group receiving the usual treatment (49, 24 and 9%, respectively), and higher rates of patients no longer using antidepressant medication (26, 16 and 0%, respectively) at 15 months. Partners taking part in the family treatments were significantly more likely to notice the improvements in the emotional health of the patient early on compared to those in the treatment as usual condition.
This study suggests that single-family and multi-family therapy may benefit hospitalized patients with major depression, and may help the partners of the patients to become aware of the patient's improvement more quickly.
基于家庭的干预措施已被证明在抑郁症治疗中有效，但很少在住院抑郁症患者中进行研究。本研究评估了在该患者群体中额外使用单家庭或多家庭团体治疗的价值。
83名患者被随机分配到：（1）常规治疗方案组（n = 23），（2）常规治疗联合单家庭治疗组（n = 25）或（3）常规治疗联合多家庭团体治疗组（n = 35）。在3个月和15个月时进行随访评估。
多家庭团体治疗组和单家庭治疗组的治疗反应率显著高于接受常规治疗的组（分别为49%、24%和9%），且在15个月时不再使用抗抑郁药物的患者比例更高（分别为26%、16%和0%）。与接受常规治疗的患者的伴侣相比，参与家庭治疗的伴侣更有可能在早期注意到患者情绪健康的改善。
本研究表明，单家庭和多家庭治疗可能使住院的重度抑郁症患者受益，并可能帮助患者的伴侣更快地意识到患者的改善。
