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慢性坏死性肺曲霉病

Chronic necrotizing pulmonary aspergillosis.

作者信息

Silva Eduardo Felipe Barbosa, Barbosa Melânio de Paula, Oliveira Marco Antônio Alves de, Martins Rosane Rodrigues, Fontinele e Silva Jefferson

机构信息

Unidade de Broncoesofagologia, Hospital de Base do Distrito Federal, Brasília, DF, Brazil.

出版信息

J Bras Pneumol. 2009 Jan;35(1):95-8. doi: 10.1590/s1806-37132009000100014.

Abstract

Chronic necrotizing pulmonary aspergillosis is one of the forms of pulmonary aspergillosis typically found in mildly immunocompromised patients. We report the case of a female patient with complaints of chronic productive cough, fever and asthenia. She reported previous corticosteroid use. A CT scan of the chest revealed consolidation with interposed cavitation in the right upper lobe. Fiberoptic bronchoscopy revealed purulent fluid within the tracheobronchial tree and an endobronchial exophytic lesion. The results of the biopsy of that lesion and the transbronchial biopsy were consistent with aspergillosis. Based on the clinical, radiological and histopathological findings, the patient was diagnosed with chronic necrotizing pulmonary aspergillosis. Treated with itraconazole, the patient presented a favorable clinical-radiological evolution.

摘要

慢性坏死性肺曲霉病是肺曲霉病的一种形式,通常见于轻度免疫功能低下的患者。我们报告一例女性患者,主诉为慢性咳痰、发热和乏力。她曾使用过皮质类固醇。胸部CT扫描显示右上叶实变并伴有空洞形成。纤维支气管镜检查发现气管支气管树内有脓性液体以及一个支气管内外生性病变。该病变活检及经支气管活检结果均符合曲霉病。根据临床、影像学和组织病理学检查结果,该患者被诊断为慢性坏死性肺曲霉病。患者接受伊曲康唑治疗后,临床和影像学表现呈良好转归。

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