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[妊娠期脓毒症和脓毒性休克:临床管理]

[Sepsis and septic shock during pregnancy: clinical management].

作者信息

Castro Eveline Oliveira de, Figueiredo Maria Rita de, Bortolotto Lemos, Zugaib Marcelo

机构信息

Departamento de Obstetrícia e Ginecologia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil.

出版信息

Rev Bras Ginecol Obstet. 2008 Dec;30(12):631-8. doi: 10.1590/s0100-72032008001200008.

Abstract

Sepsis is one of the main causes of maternal death, being related to infections from obstetric origin (infected abortion, chorioamnionitis, puerperal infection) or non-obstetric (resulting from infections which occur in other areas). This review aims at describing the mechanisms involved in the physiopathology of this entity and at updating the clinical approach to sepsis, recommended in international guidelines (early goal-directed therapy--precocious resuscitation, or precocious treatment guided by goals), as well as at calling attention to the influence of pregnancy both in the clinical manifestation and in the therapeutic management of septic conditions.

摘要

脓毒症是孕产妇死亡的主要原因之一,与产科源性感染(感染性流产、绒毛膜羊膜炎、产褥感染)或非产科源性感染(由其他部位发生的感染引起)有关。本综述旨在描述该病症病理生理学所涉及的机制,更新国际指南中推荐的脓毒症临床治疗方法(早期目标导向治疗——早期复苏或目标导向的早期治疗),并提请注意妊娠在脓毒症临床表现及治疗管理中的影响。

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