Daryaei Parviz, Vaghef Davari Farzad, Mir Mohammadreza, Harirchi Iraj, Salmasian Hojjat
Cancer Institute, Imam Khomeini Hospital, and Students' Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
World J Surg. 2009 Apr;33(4):773-7. doi: 10.1007/s00268-009-9930-8.
Surgeons routinely use nasogastric (NG) tubes in most esophageal resection surgeries. Considering the numerous complications caused by using the tube and the uncertainty about its usefulness and the scarcity of studies conducted on the subject, particularly in patients with esophageal cancer, the necessity of using the tube in these types of cases is investigated in the present study.
In this clinical trial, patients with esophageal cancer were randomized into groups with NG tube and without NG tube after surgery; the latter were prescribed metoclopramide, as well. The variables recorded for each patient included the first day of gas passage, defecation and bowel sounds (BSs) auscultation, as well as the duration of postoperative hospitalization, nausea and vomiting, abdominal distension, pulmonary complications, wound complications, anastomosis leak, and the need for placing/replacing the NG tube.
The incidence of anastomosis leak was significantly higher in the NG-tube group (6 vs. 0; P=0.016). Other complications were not different in the two groups. The mean time of gas passage, defecation, BS auscultation, and the duration of postoperative hospitalization did not have meaningful differences in the two groups. The need for placing/replacing the NG tube was the same for both groups.
The routine application of NG tubes after surgery is not recommended for all patients. We suggest that NG tubes should be used according to the specific problems of each patient.
在大多数食管癌切除手术中,外科医生通常会使用鼻胃管(NG管)。鉴于使用该管会引发诸多并发症,且其效用存在不确定性,同时针对该主题的研究稀缺,尤其是在食管癌患者中,本研究对这类病例中使用鼻胃管的必要性进行了调查。
在这项临床试验中,食管癌患者术后被随机分为使用鼻胃管组和不使用鼻胃管组;后者还开具了胃复安。记录的每位患者的变量包括首次排气、排便和肠鸣音听诊的日期,以及术后住院时间、恶心和呕吐、腹胀、肺部并发症、伤口并发症、吻合口漏,以及放置/更换鼻胃管的需求。
鼻胃管组的吻合口漏发生率显著更高(6例对0例;P = 0.016)。两组的其他并发症无差异。两组的首次排气、排便、肠鸣音听诊的平均时间以及术后住院时间均无显著差异。两组放置/更换鼻胃管的需求相同。
不建议对所有患者术后常规应用鼻胃管。我们建议应根据每位患者的具体问题使用鼻胃管。