Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, Seongnam, Korea.
Sci Rep. 2021 Jan 15;11(1):1509. doi: 10.1038/s41598-020-80825-w.
Identification of obstructive level is crucial for successful surgical outcomes in patients with obstructive sleep apnea (OSA). Unfortunately, most of the dynamic airway evaluations are performed for a short duration under drug-induced sleep; therefore, it is uncertain whether they represent airway events that occur during a whole night of sleep. This study was aimed to evaluate the correlation between obstructive levels that were identified by a short-time and a whole-night test in patients with OSA. Total 101 patients with OSA underwent drug-induced sleep fluoroscopy (DISF) and pressure manometry (PM). For DISF, the obstructive pattern was classified into one of three groups: soft palate, tongue-based, and a combined obstruction. PM was used to measure the proportion of retroglossal events out of total whole-night obstructive events in each patient. The mean age of the patients was 43.8 years. The obstructive pattern was identified as soft palate in 56 patients, combined in 38 patients, and tongue-based in 7 patients following DISF. Results from PM showed that the mean percentage of retroglossal obstructive events was 31.2 ± 30.7%. The average proportion of retroglossal obstructive events that were identified by PM in patients with soft palate, combined, and tongue-based obstruction was 27.2%, 32.1%, and 59.0%, respectively (p = 0.033). There are limitations of evaluating obstructive events that occur during a whole night with short-time tests. Surgeons should be aware the possibility of disagreement in the obstructive level between short-time and whole-night tests.
在阻塞性睡眠呼吸暂停(OSA)患者中,确定阻塞部位对于手术成功至关重要。不幸的是,大多数动态气道评估都是在药物诱导睡眠下进行短暂时间的评估;因此,无法确定它们是否代表整个睡眠期间发生的气道事件。本研究旨在评估 OSA 患者通过短时间和整夜测试确定的阻塞水平之间的相关性。共有 101 例 OSA 患者接受了药物诱导睡眠荧光透视术(DISF)和压力测压法(PM)检查。对于 DISF,阻塞模式分为三种类型之一:软腭、舌基和联合阻塞。PM 用于测量每个患者整个夜间阻塞事件中舌根事件的比例。患者的平均年龄为 43.8 岁。DISF 后,56 例患者的阻塞模式被确定为软腭,38 例为联合,7 例为舌基。PM 的结果显示,舌根阻塞事件的平均百分比为 31.2±30.7%。PM 确定的软腭、联合和舌基阻塞患者的舌根阻塞事件的平均比例分别为 27.2%、32.1%和 59.0%(p=0.033)。用短时间测试评估整个夜间发生的阻塞事件存在局限性。外科医生应该意识到短时间和整夜测试之间在阻塞水平上存在不一致的可能性。