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腹腔镜或开放手术治疗中低位直肠癌:一项非随机对照研究的短期结果

Laparoscopic or open surgery for the cancer of the middle and lower rectum short-term outcomes of a comparative non-randomised study.

作者信息

Gouvas Nikolaos, Tsiaoussis John, Pechlivanides George, Zervakis Nikolaos, Tzortzinis Anastasios, Avgerinos Costas, Dervenis Christos, Xynos Evaghelos

机构信息

Medical School, University of Crete, Crete, Greece.

出版信息

Int J Colorectal Dis. 2009 Jul;24(7):761-9. doi: 10.1007/s00384-009-0671-9. Epub 2009 Feb 17.

Abstract

INTRODUCTION

The study compares the short-term results of the laparoscopic and open approach for the surgical treatment of rectal cancer. Consecutive cases with rectal cancer operated upon with laparoscopy from 2004 to 2007 were compared to open rectal cancer cases. Total mesorectal excision (TME) was attempted in all cases.

PATIENTS AND METHODS

Forty-two cases were included in the OPEN and 45 in the LAP group and were matched for age, gender, disease stage and operation type.

SURGICAL PROCEDURE

Duration of surgery was longer and blood transfusion requirements were less in the LAP group. Higher blood loss was observed in patients with neoadjuvant treatment in both groups. Patients with neoadjuvant treatment in the OPEN group had higher operation time, but that was not the case in the LAP group. There were three conversions (7%).

RESULTS

Overall morbidity was higher in the OPEN group. LAP group patients were found to recover faster. R0 resection was achieved in 88% in the OPEN and 94% in the LAP group.

DISCUSSION

Less morbidity and faster recovery is offered after laparoscopic TME. Quality of surgery assessed by histopathology is similar between the approaches. Neoadjuvant chemoradiation seems to have significant impact on blood loss but results in longer operation times of the OPEN group.

摘要

引言

本研究比较了腹腔镜手术和开放手术治疗直肠癌的短期结果。将2004年至2007年接受腹腔镜手术的连续直肠癌病例与开放手术的直肠癌病例进行比较。所有病例均尝试行全直肠系膜切除术(TME)。

患者与方法

开放组纳入42例患者,腹腔镜组纳入45例患者,并根据年龄、性别、疾病分期和手术类型进行匹配。

手术过程

腹腔镜组手术时间较长,输血需求较少。两组接受新辅助治疗的患者失血较多。开放组接受新辅助治疗的患者手术时间较长,但腹腔镜组并非如此。有3例中转开腹(7%)。

结果

开放组总体发病率较高。发现腹腔镜组患者恢复更快。开放组R0切除率为88%,腹腔镜组为94%。

讨论

腹腔镜TME术后发病率较低且恢复更快。两种手术方式通过组织病理学评估的手术质量相似。新辅助放化疗似乎对失血有显著影响,但导致开放组手术时间延长。

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