Breen L A, Gutmann L, Brick J F, Riggs J R
Department of Neurology, West Virginia University School of Medicine, Morgantown.
Muscle Nerve. 1991 Sep;14(9):863-6. doi: 10.1002/mus.880140911.
Myasthenia gravis and Lambert-Eaton myasthenic syndrome are causes of acquired extraocular muscle weakness and ptosis. Exacerbation of ptosis after sustained upgaze is a clinically useful sign in the diagnosis of myasthenia gravis. A 54-year-old woman with established Lambert-Eaton myasthenic syndrome exhibited transient improvement of her ptosis after sustained upgaze. We suggest that paradoxical lid elevation after sustained upgaze may be a clinically useful sign in distinguishing Lambert-Eaton myasthenic syndrome from myasthenia gravis.
重症肌无力和兰伯特-伊顿肌无力综合征是后天性眼外肌无力和上睑下垂的病因。持续上视后上睑下垂加重是重症肌无力诊断中一项具有临床意义的体征。一名患有确诊兰伯特-伊顿肌无力综合征的54岁女性在持续上视后上睑下垂出现短暂改善。我们认为,持续上视后出现反常性睑裂上抬可能是在区分兰伯特-伊顿肌无力综合征和重症肌无力时一项具有临床意义的体征。