氨基磺酸铜（II）：一种用于一锅法合成3,4-二氢嘧啶-2（1H）-酮和硫酮的高效催化剂。
Copper(II) sulfamate: an efficient catalyst for the one-pot synthesis of 3,4-dihydropyrimidine-2(1H)-ones and thiones.
作者信息
Liu Chen-Jiang, Wang Ji-De
机构信息
School of Science, Xi'an Jiaotong University, Xi'an, PR China.
出版信息
Molecules. 2009 Feb 13;14(2):763-70. doi: 10.3390/molecules14020763.
Abstract
A simple, efficient procedure for the one-pot Biginelli condensation reaction of aldehydes, beta-ketoesters and urea or thiourea employing copper(II) sulfamate as a novel catalyst is described. Compared to the classical Biginelli reaction conditions, the present method has the advantages of good yields, short reaction times and experimental simplicity.
摘要
描述了一种使用氨基磺酸铜（II）作为新型催化剂，用于醛、β-酮酯与尿素或硫脲的一锅法Biginelli缩合反应的简单、高效方法。与经典的Biginelli反应条件相比，本方法具有产率高、反应时间短和实验操作简单的优点。
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