硝酸铈（Ⅲ）六水合物高效催化无溶剂合成3,4-二氢嘧啶-2（1H）-酮
Efficient Ce(NO3)3 x 6H2O-catalyzed solvent-free synthesis of 3,4-dihydropyrimidin-2(1H)-ones.
作者信息
Adib Mehdi, Ghanbary Khadijeh, Mostofi Manizheh, Ganjali Mohammad Reza
机构信息
School of Chemistry, University College of Science, University of Tehran, P. O. Box 14155-6455, Tehran, Iran.
出版信息
Molecules. 2006 Aug 23;11(8):649-54. doi: 10.3390/11080649.
Abstract
Cerium(III) nitrate hexahydrate efficiently catalyzes the three-component Biginelli reaction under solvent-free conditions of an aldehyde, a beta-keto ester or beta-diketone and urea or thiourea to afford the corresponding 3,4-dihydropyrimidin-2(1H)-ones or -thiones in excellent yields.
摘要
硝酸铈(III)六水合物在无溶剂条件下，能高效催化醛、β-酮酯或β-二酮与尿素或硫脲的三组分Biginelli反应，以优异的产率得到相应的3,4-二氢嘧啶-2(1H)-酮或-硫酮。
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