Murata K, Iwazawa T, Doki Y, Inoue M, Kaneko T, Terashima T, Mizunoya S, Okagawa K
Dept. of Surgery, Kinki Central Hospital of the Mutual Aid Association of Public School Teachers.
Gan To Kagaku Ryoho. 1989 Jul;16(7):2433-6.
The patient is a 63-year-old male with pericardial effusion who fell into cardiac tamponade one year and eight months following radical operation for esophageal cancer (stage IV). Because the cytological diagnosis for the punctured specimen of pericardial effusion indicated class V, we recognized it as pericardial recurrence and instilled CDDP 20 mg and 25 mg into the pericardial cavity. The pericardial effusion disappeared completely. There are many reports of CDDP instillation into the pleural cavity or the peritoneal cavity, but few into the pericardial cavity. For esophageal cancer, this is the first report in Japan. The patient is still alive at present after fourteen months have passed. It is considered that this method is effective for malignant pericardial effusion due to advanced esophageal cancer.
该患者为63岁男性，患有心包积液，在食管癌根治术后（IV期）1年零8个月时陷入心脏压塞。由于心包积液穿刺标本的细胞学诊断为V级，我们将其认定为心包复发，并向心包腔内注入顺铂20毫克和25毫克。心包积液完全消失。有许多关于向胸腔或腹腔内注入顺铂的报道，但向心包腔内注入的报道很少。对于食管癌，这是日本的首例报道。目前，14个月过去了，患者仍然存活。认为该方法对晚期食管癌所致恶性心包积液有效。
