Liu Yiyan
Nuclear Medicine Service, Department of Radiology, New Jersey Medical School, Newark, New Jersey, USA.
Ann Nucl Med. 2009 Feb;23(2):107-12. doi: 10.1007/s12149-008-0227-z. Epub 2009 Feb 19.
Increased ovarian or endometrial uptake may cause a dilemma in the interpretation of whole body F18-fluorodeoxyglucose-positron emission tomography (FDG-PET) imaging or even misdiagnosis of malignant disease. Knowledge of benign FDG uptake of the ovaries and uterus is important for daily practice of nuclear medicine radiologists. Increased uptake in the ovaries or uterus indicates a pathologic or neoplastic process in postmenopausal patients. In premenopausal women, increased ovarian or endometrial uptake can be functional or malignant. Benign functional uptake of premenopausal ovaries or uterus is related to the menstrual cycle; therefore, information about the patient's menstrual status is crucial for interpretation. In addition, correlation with computed tomography (CT), especially diagnostic CT acquired at the same time of PET/CT is very useful in clarifying the location of the uptake and the existence or disappearance of the discrete lesion. Increased ovarian uptake may also be identified in histologically different benign tumor entities. Nonmenstrual-related endometrial uptake may be present in many benign diseases as well.
卵巢或子宫内膜摄取增加可能会在全身F18-氟脱氧葡萄糖-正电子发射断层扫描（FDG-PET）成像的解读中造成困境，甚至可能导致恶性疾病的误诊。了解卵巢和子宫的良性FDG摄取情况对于核医学放射科医生的日常工作很重要。绝经后患者卵巢或子宫摄取增加提示存在病理或肿瘤性病变。在绝经前女性中，卵巢或子宫内膜摄取增加可能是功能性的，也可能是恶性的。绝经前卵巢或子宫的良性功能性摄取与月经周期有关；因此，患者的月经状态信息对于解读至关重要。此外，与计算机断层扫描（CT），尤其是与PET/CT同时获取的诊断性CT进行对比，对于明确摄取部位以及离散病变的存在或消失非常有用。在组织学不同的良性肿瘤实体中也可能发现卵巢摄取增加。与月经无关的子宫内膜摄取在许多良性疾病中也可能出现。
