Spiller Henry A, Griffith Jill R K
Kentucky Regional Poison Center, Louisville, KY 40232-5070, USA.
Clin Toxicol (Phila). 2009 Mar;47(3):253-5. doi: 10.1080/15563650902754877.
Information calls to poison centers, particularly for pill identification (PID), have been increasing.
Retrospective review of information calls reported to U.S. poison centers for 2002-2007.
Total number of information calls increased by 44%, while calls related to human exposures increased by 4.3%. The subcategory "pill identification" was exclusively responsible for the increase in information calls with an increase of greater than 90%. Over the 6 years, PID requests from the public, police, and healthcare facility changed by +110, +144, and -24%, respectively. PID requests from the public, police, and healthcare facility were 78, 12 and 10%, respectively. Other information calls showed a decrease or no change: calls for poison information (-17%), medical information (-2.5%), and drug information (non-PID) (+1%). Twenty-five percent of all calls to U.S. poison centers are now to identify a pill unrelated to an exposure. Sixty-four percent of all identified pills were drugs with abuse potential.
Drugs with abuse potential are less than 4% of pharmaceutical sales, yet greater than 60% of all PID requests involved drugs with abuse potential. This suggests that PID is strongly driven by interest in drugs with abuse potential.
PID calls are increasing dramatically and taxing limited poison center resources. The majority requests for identification of an unknown pill involved drugs with abuse potential.
向中毒控制中心拨打的咨询电话,尤其是关于药丸识别(PID)的电话一直在增加。
对2002 - 2007年报告给美国中毒控制中心的咨询电话进行回顾性研究。
咨询电话总数增加了44%,而与人体暴露相关的电话增加了4.3%。“药丸识别”子类别是咨询电话增加的唯一原因,增幅超过90%。在这6年中,公众、警方和医疗机构的PID请求分别变化了+110%、+144%和 - 24%。公众、警方和医疗机构的PID请求分别占78%、12%和10%。其他咨询电话呈下降或无变化:中毒信息咨询电话(-17%)、医疗信息咨询电话(-2.5%)和药物信息(非PID)咨询电话(+1%)。现在拨打给美国中毒控制中心的所有电话中有25%是为了识别与暴露无关的药丸。所有已识别的药丸中有64%是具有滥用潜力的药物。
具有滥用潜力的药物在药品销售额中占比不到4%,但在所有PID请求中,超过60%涉及具有滥用潜力的药物。这表明PID主要是由对具有滥用潜力药物的兴趣驱动的。
PID电话数量急剧增加,给中毒控制中心有限的资源带来了压力。大多数识别未知药丸的请求涉及具有滥用潜力的药物。