Lilienfeld D E, Sprafka J M, Pham D L, Baxter J
Department of Community Medicine, Mount Sinai School of Medicine, City University of New York, N.Y.
Neuroepidemiology. 1991;10(3):112-6. doi: 10.1159/000110255.
To better characterize the morbidity from Parkinson's disease and motoneuron disease, we examined hospital discharge diagnosis data for all acute care facilities (except for the Veterans Administration Medical Center) in the Minneapolis-St. Paul area in each year from 1979 to 1984 for persons aged 30-74 years. For each person in whom the discharge diagnosis included either Parkinson's disease or motoneuron disease, the age, gender, and year of admission were recorded. Annual age-gender-specific and age-adjusted gender-specific hospital discharge diagnosis rates were calculated. For Parkinson's disease, for both, men and women, the age-adjusted hospital discharge diagnosis rate declined by 26-27%. Component age-specific data for Parkinson's disease showed more variable temporal changes. For motoneuron disease, no temporal changes were observed, although the number of observations was small. These data suggest that Parkinson's disease is declining in prevalence in the hospitalized population. The implications for motoneuron disease are less clear. Further studies in this area are needed.
为了更好地描述帕金森病和运动神经元病的发病率，我们检查了1979年至1984年期间明尼阿波利斯 - 圣保罗地区所有急性护理机构（退伍军人管理局医疗中心除外）中30至74岁人群的医院出院诊断数据。对于出院诊断包括帕金森病或运动神经元病的每个人，记录其年龄、性别和入院年份。计算了年度年龄 - 性别特异性和年龄调整后的性别特异性医院出院诊断率。对于帕金森病，男性和女性的年龄调整后医院出院诊断率均下降了26 - 27%。帕金森病的特定年龄组成数据显示出更具变化性的时间变化。对于运动神经元病，尽管观察数量较少，但未观察到时间变化。这些数据表明，住院人群中帕金森病的患病率正在下降。运动神经元病的影响尚不清楚。该领域需要进一步研究。
