Kamada K, Isu T, Houkin K, Ohsato T, Katoh M, Kojima H
Department of Neurosurgery, Kushiro Rousai Hospital, Hokkaido, Japan.
Neurosurgery. 1991 Sep;29(3):464-6. doi: 10.1097/00006123-199109000-00025.
The authors present a case of acute aggravation of subdural effusion associated with pachymeningitis carcinomatosa. Microscopic examination of a surgical specimen revealed diffuse involvement of the dura mater by a metastatic adenocarcinoma in which the tumor cells invaded venules located in the areolar layer in particular. The rapid increase in capillary transmural pressure resulted in extravasation of plasma components, causing an increase in subdural effusion.
作者报告了一例与癌性硬脑膜炎相关的硬膜下积液急性加重病例。手术标本的显微镜检查显示硬脑膜被转移性腺癌弥漫性累及，其中肿瘤细胞尤其侵犯位于疏松结缔组织层的小静脉。毛细血管跨壁压力的快速增加导致血浆成分外渗，引起硬膜下积液增加。
