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一例桥脑下部海绵状血管瘤,表现为单侧颅神经麻痹和节段性感觉障碍的亚急性起病

[A case of cavernous angioma in the lower pons, showing subacute onset of unilateral cranial nerve palsy and segmental sensory disturbance].

作者信息

Yamamoto Ryoo, Nishiyama Takehiko, Kurokawa Takashi, Hakii Yasuhito, Kishida Hitaru, Kuroiwa Yoshiyuki

机构信息

Department of Clinical Neurology, Graduate School of Medical Sciences, Yokohama City University.

出版信息

Rinsho Shinkeigaku. 2009 Jan;49(1):32-6. doi: 10.5692/clinicalneurol.49.32.

Abstract

We report a 54-year-old man with right abducent nerve palsy, right facial nerve palsy, and left segmental sensory disturbance, which progressed for 2 weeks. He was found to have cavernous angioma in the lower pons. When he visited our hospital, he had right facial palsy, sensory disturbance of left half of the face and left upper limb, and diplopia. He had suffered right abducent nerve palsy 5 years previously and had recently developed hypertension. Neurological examination further revealed right abducent nerve palsy, right peripheral facial nerve palsy, sensory impairment of the left half of the face, and sensory impairment on the left side from C2 to Th3. Magnetic resonance imaging of the head revealed hemorrhage with a rim at the right dorsal part of the lower pons. No abnormalities were identified on cerebral angiography. He was diagnosed as having hemorrhage originating from a cavernous angioma. We assumed that the segmental sensory disturbance was caused by medial involvement of the lateral spinothalamic tract, which is somatotopically arranged: the fibers from the sacral segments being most lateral. The ventral trigeminothalamic tract, right abducent nerve, and right facial nerve were also disturbed. Segmental sensory disturbance usually accompanies a spinal cord lesion. But several cases with similar symptoms following a brainstem lesion have been reported. Most of them had stroke, showing acute onset of illness. Our case showed subacute onset of illness; cranial nerve palsy and segmental sensory disturbance progressed for 2 weeks.

摘要

我们报告一名54岁男性,患有右侧展神经麻痹、右侧面神经麻痹和左侧节段性感觉障碍,病程持续2周。他被发现脑桥下部有海绵状血管瘤。他来我院就诊时,存在右侧面神经麻痹、左侧面部及左侧上肢感觉障碍和复视。他5年前曾患右侧展神经麻痹,近期出现高血压。神经系统检查进一步发现右侧展神经麻痹、右侧周围性面神经麻痹、左侧面部感觉障碍以及左侧从C2至Th3节段感觉障碍。头部磁共振成像显示脑桥下部右侧背侧有带边缘的出血。脑血管造影未发现异常。他被诊断为海绵状血管瘤出血。我们推测节段性感觉障碍是由外侧脊髓丘脑束内侧受累所致,该束按躯体定位排列:来自骶节段的纤维最靠外侧。腹侧三叉丘脑束、右侧展神经和右侧面神经也受到了干扰。节段性感觉障碍通常伴有脊髓病变。但已有数例脑干病变后出现类似症状的病例报道。其中大多数为中风,起病急。我们的病例起病亚急性;脑神经麻痹和节段性感觉障碍持续进展了2周。

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