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脑干肿瘤手术治疗后出现严重体位性低血压患者的保守康复治疗:病例说明

Conservative rehabilitation for a patient presenting with severe orthostatic hypotension after surgical management of brainstem tumor: illustrative case.

作者信息

Nagumo Misato, Tashiro Syoichi, Hijikata Nanako, Ishikawa Aiko, Akiyama Takenori, Tsuji Tetsuya

机构信息

Departments of Rehabilitation Medicine and.

Neurosurgery, Keio University School of Medicine, Tokyo, Japan; and.

出版信息

J Neurosurg Case Lessons. 2021 Jun 21;1(25):CASE2136. doi: 10.3171/CASE2136.

DOI:10.3171/CASE2136
PMID:35855083
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9245778/
Abstract

BACKGROUND

Blood pressure (BP) dysregulation is frequently observed in patients after surgical management of brainstem lesions; however, there has been no standard rehabilitation. Considering the conflicting risks for hypoperfusion and disuse syndrome in these patients, a safe and effective rehabilitative strategy is warranted.

OBSERVATIONS

A 50-year-old man who had undergone craniotomy for resection of a recurrent dorsal medullary epidermoid cyst developed persistent orthostatic hypotension. It was resistant to physical exercise, pharmacological therapy, abdominal binders, and compression stockings; therefore, it inhibited postoperative rehabilitation. Although the responsible lesion was not clearly visible on the postoperative image, accompanying symptoms, including segmental sensory impairment, implied an improvement in BP control. Although there was a trade-off between the risk of developing disuse syndrome and a delay in functional recovery, the authors decided to continue a conservative rehabilitation strategy rather than increasing the workload. The patient's BP control was gradually restored by the seventh postoperative week, and the authors proceeded with basic activity training.

LESSONS

A conservative prognostic prediction-based rehabilitation strategy was applied in this case. The precise evaluation of the accompanying neurological symptoms was helpful in deciding the treatment regimen. The conflicting risks for hypoperfusion and disuse syndrome in such cases must be considered.

摘要

背景

脑干病变手术治疗后的患者经常出现血压调节异常;然而,目前尚无标准的康复方法。鉴于这些患者存在灌注不足和废用综合征的矛盾风险,有必要制定一种安全有效的康复策略。

观察结果

一名50岁男性因复发性延髓背侧表皮样囊肿行开颅切除术,术后出现持续性直立性低血压。该症状对体育锻炼、药物治疗、腹部捆绑和弹力袜均无反应;因此,它阻碍了术后康复。尽管术后影像上无法清晰看到责任病灶,但包括节段性感觉障碍在内的伴随症状提示血压控制有所改善。尽管在发生废用综合征的风险与功能恢复延迟之间存在权衡,但作者决定继续采用保守的康复策略,而非增加训练量。术后第7周,患者的血压控制逐渐恢复,作者随后开展了基本活动训练。

经验教训

本例采用了基于保守预后预测的康复策略。对伴随神经症状的精确评估有助于确定治疗方案。在此类病例中,必须考虑灌注不足和废用综合征的矛盾风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4293/9245778/eb51399969ec/CASE2136f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4293/9245778/6ccd68011f28/CASE2136f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4293/9245778/eb51399969ec/CASE2136f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4293/9245778/6ccd68011f28/CASE2136f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4293/9245778/eb51399969ec/CASE2136f2.jpg

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Conservative rehabilitation for a patient presenting with severe orthostatic hypotension after surgical management of brainstem tumor: illustrative case.脑干肿瘤手术治疗后出现严重体位性低血压患者的保守康复治疗:病例说明
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本文引用的文献

1
Orthostatic Hypotension and Falls in Older Adults: A Systematic Review and Meta-analysis.老年人直立性低血压与跌倒:系统评价和荟萃分析。
J Am Med Dir Assoc. 2019 May;20(5):589-597.e5. doi: 10.1016/j.jamda.2018.11.003. Epub 2018 Dec 21.
2
Evidence-based treatment of neurogenic orthostatic hypotension and related symptoms.神经源性直立性低血压及相关症状的循证治疗。
J Neural Transm (Vienna). 2017 Dec;124(12):1567-1605. doi: 10.1007/s00702-017-1791-y. Epub 2017 Oct 22.
3
Refractory Orthostatic Hypotension Caused by a Recurrent Hemangioblastoma: Case Report and Review of the Literature.
复发性血管母细胞瘤所致难治性直立性低血压:病例报告及文献复习
Cureus. 2016 Mar 24;8(3):e540. doi: 10.7759/cureus.540.
4
Autonomic dysfunction elicited by a medulla oblongata injury after fourth ventricle tumor surgery in a pediatric patient.一名儿科患者在第四脑室肿瘤手术后因延髓损伤引发自主神经功能障碍。
Auton Neurosci. 2016 Jan;194:52-7. doi: 10.1016/j.autneu.2015.12.002. Epub 2015 Dec 4.
5
Middle Cerebral Artery Occlusion Presenting as Upper Limb Monochorea.表现为上肢单发性舞蹈症的大脑中动脉闭塞
J Stroke Cerebrovasc Dis. 2015 Oct;24(10):e291-3. doi: 10.1016/j.jstrokecerebrovasdis.2015.06.009. Epub 2015 Aug 17.
6
Nonpharmacologic management of orthostatic hypotension: a systematic review.非药物治疗直立性低血压:系统评价。
Arch Phys Med Rehabil. 2015 Feb;96(2):366-375.e6. doi: 10.1016/j.apmr.2014.09.028. Epub 2014 Oct 14.
7
Orthostatic hypotension following resection of a dorsal medullary hemangioblastoma.直立性低血压在背髓血管母细胞瘤切除术后发生。
Neurocrit Care. 2012 Apr;16(2):306-10. doi: 10.1007/s12028-011-9656-y.
8
Bilateral bulbar palsy and postural hypotension following surgery for fourth ventricle subependymoma.第四脑室室管膜下瘤手术后出现双侧球麻痹和体位性低血压。
J Clin Neurosci. 2009 Dec;16(12):1646-8. doi: 10.1016/j.jocn.2009.02.017. Epub 2009 Sep 18.
9
[A case of cavernous angioma in the lower pons, showing subacute onset of unilateral cranial nerve palsy and segmental sensory disturbance].一例桥脑下部海绵状血管瘤,表现为单侧颅神经麻痹和节段性感觉障碍的亚急性起病
Rinsho Shinkeigaku. 2009 Jan;49(1):32-6. doi: 10.5692/clinicalneurol.49.32.
10
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Clin Rehabil. 2008 Dec;22(12):1034-41. doi: 10.1177/0269215508092821.