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[双侧展神经麻痹继发于脑桥出血所致的假性手足徐动症——临床及神经放射学研究]

[Bilateral abducens nerve palsy followed by pseudoathetosis due to pontine hemorrhage--clinical and neuroradiological study].

作者信息

Waragai M, Iwabuchi S, Niwa N

机构信息

Department of Neurology, Stroke Center, Nanasawa Rehabilitation Hospital.

出版信息

Rinsho Shinkeigaku. 1993 May;33(5):546-51.

PMID:8365063
Abstract

Reported here are two cases with pontine hemorrhage presented with bilateral abducens nerve palsy and followed by pseudoathetosis, ataxia, and hemiparesis on the contralateral side of the lesion. The first case, a 57-year-old man, who suffered from bilateral abducens nerve palsy, deafness and hypoesthesia, ataxia, and hemiparesis of the right side of the body. MRI showed the confined lesion in the left side of tegmentum at the level of middle pons. When the abducens nerve palsy began to improve, pseudoathetosis of the right fingers appeared. About six months later, symptoms almost recovered, except for ataxia. The second case, a 48-year-old man who suffered from bilateral abducens nerve palsy, deafness of the left ear, and ataxia, hypoesthesia, and hemiparesis of the left side of the body was admitted. MRI disclosed a small lesion on the right side of the tegmentum at the level of middle pons. When the bilateral abducens nerve palsy was beginning to improve, pseudoathetosis of the left hand appeared. Three months later, pseudoathetosis of the left hand disappeared. Both patients presented here had a similar lesion in the tegmentum at the level of middle pons on the side contralateral to the side in which the pseudoathetosis was seen. Considering the clinical symptoms and radiological findings of these cases, it appears that a lesion which causes such rare neurological symptoms may involve the medial lemniscus, spinothalamic tract, lateral lemniscus, spinocerebellar fiber, and central tegmental tract at the tegmentum of the middle pons on the side contralateral to the cerebellar signs and pseudoathetosis.

摘要

本文报告了两例桥脑出血病例,均表现为双侧展神经麻痹,随后出现假手足徐动症、共济失调及病变对侧偏瘫。第一例为一名57岁男性,患有双侧展神经麻痹、耳聋、感觉减退、共济失调及右侧肢体偏瘫。MRI显示中脑桥水平左侧被盖部局限性病变。当展神经麻痹开始改善时,右侧手指出现假手足徐动症。约6个月后,除共济失调外,症状几乎完全恢复。第二例为一名48岁男性,患有双侧展神经麻痹、左耳耳聋、共济失调、左侧肢体感觉减退及偏瘫。MRI显示中脑桥水平右侧被盖部有一小病变。当双侧展神经麻痹开始改善时,左手出现假手足徐动症。3个月后,左手假手足徐动症消失。本文报道的这两名患者在出现假手足徐动症一侧的对侧中脑桥水平被盖部有相似病变。综合这些病例的临床症状和影像学表现,似乎导致这些罕见神经症状的病变可能累及中脑桥被盖部与小脑体征及假手足徐动症对侧的内侧丘系、脊髓丘脑束、外侧丘系、脊髓小脑纤维和中央被盖束。

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