Angelo Laura S, Kurzrock Razelle
Department of Investigational Cancer Therapeutics (Phase I Clinical Trials Program), Division of Cancer Medicine, M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
Clin Cancer Res. 2009 Feb 15;15(4):1123-5. doi: 10.1158/1078-0432.CCR-08-2791.
Two naturally occurring compounds, curcumin, the active ingredient in the spice turmeric, and the green tea extract epigallocatechin-3-gallate, have marked effects on the apoptotic machinery in chronic lymphocytic leukemia. These results provide a preclinical foundation for future clinical use of these compounds in this disease.
两种天然存在的化合物,即姜黄(一种香料)中的活性成分姜黄素以及绿茶提取物表没食子儿茶素没食子酸酯,对慢性淋巴细胞白血病的凋亡机制有显著影响。这些结果为这些化合物未来在该疾病中的临床应用提供了临床前基础。