Garnica-Garza H M
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional Unidad Monterrey, Vía del Conocimiento 201 Parque de Investigación e Innovación Tecnológica, Apodaca NL C.P. 66600, Mexico.
Phys Med Biol. 2009 Mar 21;54(6):1621-31. doi: 10.1088/0031-9155/54/6/015. Epub 2009 Feb 19.
Monte Carlo simulation was employed to calculate the response of TLD-100 chips under irradiation conditions such as those found during accelerated partial breast irradiation with the MammoSite radiation therapy system. The absorbed dose versus radius in the last 0.5 cm of the treated volume was also calculated, employing a resolution of 20 microm, and a function that fits the observed data was determined. Several clinically relevant irradiation conditions were simulated for different combinations of balloon size, balloon-to-surface distance and contents of the contrast solution used to fill the balloon. The thermoluminescent dosemeter (TLD) cross-calibration factors were derived assuming that the calibration of the dosemeters was carried out using a Cobalt 60 beam, and in such a way that they provide a set of parameters that reproduce the function that describes the behavior of the absorbed dose versus radius curve. Such factors may also prove to be useful for those standardized laboratories that provide postal dosimetry services.
采用蒙特卡罗模拟方法计算了TLD - 100芯片在诸如使用MammoSite放射治疗系统进行加速部分乳腺照射期间所发现的辐照条件下的响应。还计算了治疗体积最后0.5厘米内吸收剂量与半径的关系，分辨率为20微米，并确定了拟合观测数据的函数。针对球囊大小、球囊与表面距离以及用于填充球囊的造影剂溶液含量的不同组合，模拟了几种临床相关的辐照条件。热释光剂量计（TLD）交叉校准因子是在假设剂量计校准使用钴60束进行的情况下得出的，并且以这样一种方式得出，即它们提供一组参数，这些参数可重现描述吸收剂量与半径曲线行为的函数。这些因子对于提供邮政剂量测定服务的标准化实验室可能也很有用。
