Roydhouse N
Department of Otolaryngology, Middlemore Hospital, Auckland.
N Z Med J. 1991 Sep 11;104(919):380-2.
There are various forms of medical treatment for otitis media with effusion (OME) in children. One of these is a four week course of an antibiotic. A trial was carried out comparing cotrimoxazole with amoxicillin-potassium clavulanate in 102 cases with 181 affected ears. In addition this trial used various procedures to increase and monitor compliance, and the results showed that the compliant cases did much better than the noncompliant cases and cotrimoxazole was more effective than amoxicillin-potassium clavulanate. When the ethnic groupings were analysed the compliance was lower for the Maori (24%) and Pacific Islander (29%) than the European (49%). The success rate for the compliant cases whose middle ear effusion resolved in one or both ears had a similar result with Maori (40%), Pacific Islander (60%) and European (71%) probably indicating an increased nonmeasured compliance in the latter.
儿童分泌性中耳炎（OME）有多种医学治疗形式。其中一种是为期四周的抗生素疗程。一项试验对102例、共181只患耳的儿童进行了比较复方新诺明与阿莫西林-克拉维酸钾疗效的研究。此外，该试验采用了多种方法来提高并监测依从性，结果显示，依从性好的病例比不依从的病例效果好得多，且复方新诺明比阿莫西林-克拉维酸钾更有效。在对不同种族进行分析时发现，毛利人（24%）和太平洋岛民（29%）的依从性低于欧洲人（49%）。中耳积液在一只或两只耳朵中消退的依从性好的病例的成功率在毛利人（40%）、太平洋岛民（60%）和欧洲人（71%）中结果相似，这可能表明后者存在未测量到的依从性增加情况。
