血红蛋白对滴滴涕的还原脱氯作用。

Reductive dechlorination of DDT by haem proteins.

作者信息

Stotter D A, Thomas R D, Wilson M T

出版信息

Bioinorg Chem. 1977;7(1):87-93. doi: 10.1016/s0006-3061(00)80130-1.

PMID:192320

Abstract

DDT1 is converted to DDD by reduced myoglobin (rapidly), cytochrome c oxidase, and a haem-containing undecapeptide derived from cytochrome c. Cytochrome c itself is inactive. This demonstrates that an accessible haem site is necessary for the reaction. Spectrophotometric evidence is presented for an interaction between DDT and the undecapeptide. These results cast light on one of the biological pathways for the breakdown of DDT.

摘要

DDT1通过还原型肌红蛋白（快速地）、细胞色素c氧化酶以及一种源自细胞色素c的含血红素的十一肽被转化为DDD。细胞色素c本身无活性。这表明反应需要一个可及的血红素位点。给出了关于DDT与该十一肽之间相互作用的分光光度法证据。这些结果揭示了DDT分解的一种生物学途径。