Stafford Lesley, Berk Michael, Jackson Henry J
Department of Psychology, University of Melbourne, Melbourne, Australia.
J Psychosom Res. 2009 Mar;66(3):211-20. doi: 10.1016/j.jpsychores.2008.09.005. Epub 2008 Dec 17.
Depression occurs commonly in coronary artery disease (CAD) and is associated with substantial disability. Modifiable cognitive determinants of depression in this population have not been identified. We investigated the impact of potentially modifiable illness beliefs about CAD on depressive symptomatology. We also examined the association between these beliefs and health-related quality of life (HRQOL) and socio-demographic variations in illness beliefs.
A prospective study of 193 recently hospitalized CAD patients was conducted. Data were collected from medical records and by self-report 3 and 9 months post-discharge. Socio-demographic differences were analysed with independent sample t-tests. Predictive models were tested in a series of hierarchical linear regression equations that controlled for known clinical, psychosocial, and demographic correlates of outcome.
Negative illness beliefs, particularly those associated with the consequences of CAD, were significantly predictive of higher levels of depressive symptomatology at 3 and 9 months. Positive illness perceptions were significantly associated with better HRQOL outcomes. Older and less socially advantaged patients demonstrated more negative illness beliefs.
Illness beliefs are significantly associated with depressive symptomatology and HRQOL in CAD patients. These beliefs can be easily identified and constitute a meaningful and clinically accessible avenue for improving psychological morbidity and HRQOL in CAD patients. Older and more socially vulnerable patients may require heightened monitoring of their illness beliefs. Research needs to translate these and other predictive findings into interventions.
抑郁症在冠状动脉疾病(CAD)中普遍存在,且与严重残疾相关。尚未确定该人群中抑郁症可改变的认知决定因素。我们研究了关于CAD的潜在可改变的疾病信念对抑郁症状的影响。我们还研究了这些信念与健康相关生活质量(HRQOL)之间的关联以及疾病信念中的社会人口学差异。
对193名近期住院的CAD患者进行了一项前瞻性研究。在出院后3个月和9个月通过病历和自我报告收集数据。使用独立样本t检验分析社会人口学差异。在一系列分层线性回归方程中测试预测模型,这些方程控制了已知的临床、心理社会和人口统计学相关结果。
消极的疾病信念,尤其是那些与CAD后果相关的信念,在3个月和9个月时显著预测了更高水平的抑郁症状。积极的疾病认知与更好的HRQOL结果显著相关。年龄较大且社会优势较低的患者表现出更多消极的疾病信念。
疾病信念与CAD患者的抑郁症状和HRQOL显著相关。这些信念很容易识别,是改善CAD患者心理发病率和HRQOL的有意义且临床上可行的途径。年龄较大且社会更脆弱的患者可能需要加强对其疾病信念的监测。研究需要将这些及其他预测性发现转化为干预措施。