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消极的疾病认知与甲状腺癌幸存者的健康相关生活质量较差有关:来自 PROFILES 登记处的结果。

Negative illness perceptions are related to poorer health-related quality of life among thyroid cancer survivors: Results from the PROFILES registry.

机构信息

CoRPS-Center of Research on Psychological and Somatic disorders, Department of Medical and Clinical Psychology, Tilburg University, Tilburg, The Netherlands.

Department of Internal Medicine, Maxima Medical Centre, Eindhoven, The Netherlands.

出版信息

Head Neck. 2020 Sep;42(9):2533-2541. doi: 10.1002/hed.26290. Epub 2020 Jun 3.

Abstract

BACKGROUND

Differentiated thyroid cancer (DTC) reports a poorer health-related quality of life (HRQoL) than a norm population. Patients' illness perceptions are modifiable and known associates of HRQoL in other cancers. The aim was to examine the relationship between illness perceptions and HRQoL among DTC survivors.

METHODS

DTC survivors registered in the Netherlands Cancer Registry diagnosed between 1990 and 2008, received a survey on illness perceptions (Brief-Illness Perception Questionnaire; B-IPQ) and HRQoL (European Organisation for Research and Treatment of Cancer, Quality of Life Questionnaire-Core 30; EORTC QLQ-C30). Multiple regression analyses were conducted investigating the relation between illness perceptions and HRQoL, while controlling for sociodemographic and clinical characteristics.

RESULTS

Two hundred and eighty-four DTC survivors were included. DTC survivors who believed their illness had many negative consequences; who perceived their illness as controllable by treatment; who had strong beliefs symptoms could be attributed to their illness; and who had strong beliefs their illness causes negative emotions, reported a poorer HRQoL.

CONCLUSIONS

Stronger negative illness perceptions are related to a poorer HRQoL among DTC survivors.

摘要

背景

分化型甲状腺癌(DTC)患者的健康相关生活质量(HRQoL)比一般人群差。患者的疾病认知是可改变的,并且已知与其他癌症的 HRQoL 有关。本研究旨在探讨 DTC 幸存者的疾病认知与 HRQoL 之间的关系。

方法

荷兰癌症登记处登记的 1990 年至 2008 年间诊断为 DTC 的幸存者,接受了关于疾病认知(简要疾病认知问卷;B-IPQ)和 HRQoL(欧洲癌症研究与治疗组织,生活质量问卷核心 30 个问题;EORTC QLQ-C30)的调查。进行了多变量回归分析,以研究疾病认知与 HRQoL 之间的关系,同时控制社会人口学和临床特征。

结果

共纳入 284 名 DTC 幸存者。DTC 幸存者认为自己的疾病有许多负面后果;认为自己的疾病可以通过治疗控制;认为自己的症状是由疾病引起的;认为疾病会引起负面情绪,他们的 HRQoL 较差。

结论

更强的负面疾病认知与 DTC 幸存者较差的 HRQoL 有关。

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