Chan C C, Palestine A G, Davis J L, de Smet M D, McLean I W, Burnier M, Drouilhet J H, Nussenblatt R B
Laboratory of Immunology, National Eye Institute, Bethesda, MD 20892.
Ophthalmology. 1991 Aug;98(8):1281-6. doi: 10.1016/s0161-6420(91)32142-0.
Two patients who had similar clinical presentations of bilateral multiple chorioretinal lesions and needed a correct diagnosis underwent chorioretinal biopsy. The biopsy from one patient demonstrated mainly a B cell infiltrate in choroidal and subretinal nodules, while the biopsy from the second patient showed mainly macrophages in the retina. These findings directed the therapeutic approach taken in each patient. Although chorioretinal biopsy is an invasive procedure with the potential for serious complications, the resultant finding may aid in the diagnosis and guide the subsequent management of certain patients presenting with serious ocular findings of undefined etiology.
两名临床表现为双侧多发性脉络膜视网膜病变且需要明确诊断的患者接受了脉络膜视网膜活检。其中一名患者的活检显示脉络膜和视网膜下结节主要有B细胞浸润，而另一名患者的活检显示视网膜主要为巨噬细胞。这些发现指导了对每名患者采取的治疗方法。尽管脉络膜视网膜活检是一种有严重并发症风险的侵入性操作，但所得结果可能有助于诊断，并指导后续对某些病因不明的严重眼部表现患者的管理。
