[大鼠肝癌27和詹森肉瘤中心磷脂的生物合成]
[Biosynthesis of cardiolipin in the rat hepatoma 27 and Jensen sarcoma].
作者信息
Diatlovntskaia E V, Khostetler K I, Einisman L I, Gorbkova N P
出版信息
Biokhimiia. 1976 Aug;41(8):1421-5.
PMID:192337
Abstract
The localization of cardiolipin biosynthesis in rat hepatoma 27 and Jensen sarcoma cells was investigated. In both tumors cardiolipin was found to be synthesized only in the mitochondria as is the case in normal rat liver. It is concluded that the occurrence of cardiolipin in the microsomes of the tumor cells may be connected with a transmembrane exchange of phospholipids in vivo.
摘要
对大鼠肝癌27细胞和詹森肉瘤细胞中心磷脂生物合成的定位进行了研究。在这两种肿瘤中，发现心磷脂仅在线粒体中合成，这与正常大鼠肝脏的情况相同。得出的结论是，肿瘤细胞微粒体中心磷脂的出现可能与体内磷脂的跨膜交换有关。
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