Balla Vamsi Krishna, DeVasConCellos Paul Duteil, Xue Weichang, Bose Susmita, Bandyopadhyay Amit
W. M. Keck Biomedical Materials Research Laboratory, School of Mechanical and Materials Engineering, Washington State University, Pullman, WA 99164-2920, USA.
Acta Biomater. 2009 Jun;5(5):1831-7. doi: 10.1016/j.actbio.2009.01.011. Epub 2009 Jan 22.
Novel structures with functional gradation in composition and structure were successfully made in Ti-TiO(2) combination using laser engineered net shaping. The addition of fully dense, compositionally graded TiO(2) ceramic on porous Ti significantly increased the surface wettability and hardness. The graded structures with varying concentrations of TiO(2) on the top surface were found to be non-toxic and biocompatible. In addition, the higher wettability of surfaces with TiO(2) can enhance their ability to form chemisorbed lubricating films, which can potentially lower the friction coefficient against ultrahigh molecular weight polyethylene liner, thus reducing its wear rate. These unitized structures with open porosity on one side and hard, low friction surface on the other side can eliminate the need for multiple parts with different compositions for load-bearing implants such as total hip prostheses.
利用激光工程化净成形技术，成功地在钛-二氧化钛组合材料中制造出了成分和结构具有功能梯度的新型结构。在多孔钛上添加完全致密、成分渐变的二氧化钛陶瓷，显著提高了表面润湿性和硬度。发现顶面上具有不同二氧化钛浓度的梯度结构无毒且具有生物相容性。此外，含有二氧化钛的表面具有更高的润湿性，这可以增强其形成化学吸附润滑膜的能力，从而有可能降低与超高分子量聚乙烯衬垫之间的摩擦系数，进而降低其磨损率。这些一侧具有开放孔隙率、另一侧具有坚硬低摩擦表面的一体化结构，可消除全髋关节假体等承重植入物对多种不同成分部件的需求。
