Voskoboev A I, Chernikevich I P
Biokhimiia. 1977 Jan;42(1):79-84.
The interaction of thiamine pyrophosphokinase (Thiaminkinase EC 2.7.6.2) with thiamine and ATP was studied. It was shown that the mechanism of the thiaminokinase reactions is Rapid Equilibrium Random Bi -- Bi. The enzyme binds 8 moles ATP and 1 mole thiamine per mole protein Ks = 0,8-10(-3) and 4.10(-6) M for ATP and thiamine respectively.
对硫胺素焦磷酸激酶（硫胺素激酶，EC 2.7.6.2）与硫胺素和ATP的相互作用进行了研究。结果表明，硫胺素激酶反应的机制是快速平衡随机双双反应。该酶每摩尔蛋白质结合8摩尔ATP和1摩尔硫胺素，ATP和硫胺素的Ks分别为0.8×10⁻³和4.1×10⁻⁶M。
