Zakahrov Iu M, Rassokhin A G, Krest'ianinova O G, Efimenko G P
Patol Fiziol Eksp Ter. 1991 May-Jun(3):36-8.
Stimulation and inhibition of erythropoiesis were modelled in rats to study the functional condition of central macrophages of the erythroblastic islets (EI) in the bone marrow by determining the total content of lysosomes, pH of lysosomes, activity of acid phosphatase, and 3H-thymidine inclusion in DNA. The properties of the surface charges of the EI cells were judged according to the electrophoretic mobility, the number of acid glycoproteins--according to the staining of the preparations with alcian blue. It is shown that the intensity of erythropoiesis in the EI determines the studied values. Sensitivity of EI macrophages to erythropoietin was demonstrated in EI cultivation.
在大鼠中对红细胞生成的刺激和抑制进行建模，通过测定溶酶体的总含量、溶酶体的pH值、酸性磷酸酶的活性以及DNA中3H-胸腺嘧啶核苷的掺入量，来研究骨髓中红细胞生成岛（EI）中央巨噬细胞的功能状态。根据电泳迁移率判断EI细胞表面电荷的性质，根据阿尔辛蓝对制剂的染色判断酸性糖蛋白的数量。结果表明，EI中红细胞生成的强度决定了所研究的值。在EI培养中证明了EI巨噬细胞对促红细胞生成素的敏感性。
