DC-SIGN and alpha2,6-sialylated IgG Fc interaction is dispensable for the anti-inflammatory activity of IVIg on human dendritic cells.
作者信息
Bayry Jagadeesh, Bansal Kushagra, Kazatchkine Michel D, Kaveri Srini V
出版信息
Proc Natl Acad Sci U S A. 2009 Mar 3;106(9):E24; author reply E25. doi: 10.1073/pnas.0900016106. Epub 2009 Feb 23.
Abstract
摘要
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DC-SIGN and alpha2,6-sialylated IgG Fc interaction is dispensable for the anti-inflammatory activity of IVIg on human dendritic cells.DC-SIGN与α2,6-唾液酸化IgG Fc的相互作用对于静脉注射免疫球蛋白对人树突状细胞的抗炎活性而言并非必需。
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本文引用的文献
1
Identification of a receptor required for the anti-inflammatory activity of IVIG.鉴定静脉注射免疫球蛋白抗炎活性所需的一种受体。
Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19571-8. doi: 10.1073/pnas.0810163105. Epub 2008 Nov 26.
2
Recapitulation of IVIG anti-inflammatory activity with a recombinant IgG Fc.用重组IgG Fc概括静脉注射免疫球蛋白的抗炎活性。
Science. 2008 Apr 18;320(5874):373-6. doi: 10.1126/science.1154315.
3
Anti-inflammatory actions of intravenous immunoglobulin.静脉注射免疫球蛋白的抗炎作用。
Annu Rev Immunol. 2008;26:513-33. doi: 10.1146/annurev.immunol.26.021607.090232.
4
Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action.单克隆抗体和静脉注射免疫球蛋白治疗风湿性疾病：理论依据与作用机制
Nat Clin Pract Rheumatol. 2007 May;3(5):262-72. doi: 10.1038/ncprheum0481.
5
Natural antibodies sustain differentiation and maturation of human dendritic cells.天然抗体维持人类树突状细胞的分化和成熟。
Proc Natl Acad Sci U S A. 2004 Sep 28;101(39):14210-5. doi: 10.1073/pnas.0402183101. Epub 2004 Sep 20.
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