Department of Medicine, Baylor College of Medicine, One Baylor Plaza, BCM Mailstop 285, Houston, TX 77030, USA.
Dig Dis Sci. 2010 Feb;55(2):233-9. doi: 10.1007/s10620-009-0750-3. Epub 2009 Feb 24.
Hematochezia, defined as the passage of blood or clots from the rectum, is common and can be quite alarming. Few patients in general consult their physicians for this symptom. Various reasons have been explored for this behavior. Physician attitudes also shed some light onto why some patients are referred and others are not. Hematochezia may be associated with an anal cause in most healthy young adults (<50 years of age), but some may end up being diagnosed with colorectal cancer (CRC). Many studies have looked at the usefulness of clinical presentation in helping to decide which patients need further evaluation and what the optimal mode of investigation should be. Of note, studies on patients less than 50 years of age presenting with rectal bleeding have been few and far between. The results of these studies have been contradictory to the point where, today, there is no single set of consensus guidelines on the approach to hematochezia in young patients. In this review, the value of clinical symptoms and the underlying risk of CRC in guiding this clinical decision will be discussed.
血便,即血液或凝块从直肠排出,较为常见,可能令人十分担忧。一般来说,很少有患者因该症状而咨询医生。人们已经探讨了导致这种行为的各种原因。医生的态度也揭示了为什么有些患者会被转介,而有些则不会。在大多数健康的年轻成年人(<50 岁)中,血便可能与肛门原因有关,但有些患者最终可能被诊断为结直肠癌(CRC)。许多研究都探讨了临床表现在帮助确定哪些患者需要进一步评估以及最佳的检查方式方面的作用。值得注意的是,关于年龄<50 岁的患者出现直肠出血的研究很少。这些研究的结果相互矛盾,以至于目前,对于年轻患者血便的处理方法尚无一套统一的共识指南。在本次综述中,将讨论临床症状的价值以及 CRC 的潜在风险在指导这一临床决策中的作用。