Is low histamine a fundamental cause of sleepiness in narcolepsy and idiopathic hypersomnia?
作者信息
Scammell Thomas E, Mochizuki Takatoshi
机构信息
Department of Neurology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, El CLS-705, Boston, MA 02215, USA.
出版信息
Sleep. 2009 Feb;32(2):133-4. doi: 10.1093/sleep/32.2.133.
Abstract
摘要
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本文引用的文献
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Sleep. 2009 Feb;32(2):181-7. doi: 10.1093/sleep/32.2.181.
2
Decreased CSF histamine in narcolepsy with and without low CSF hypocretin-1 in comparison to healthy controls.与健康对照组相比，伴或不伴脑脊液中低食欲素-1的发作性睡病患者脑脊液中组胺减少。
Sleep. 2009 Feb;32(2):175-80. doi: 10.1093/sleep/32.2.175.
3
Brain histamine H1 receptor occupancy of orally administered antihistamines, bepotastine and diphenhydramine, measured by PET with 11C-doxepin.通过使用11C-多塞平的正电子发射断层扫描（PET）测量口服抗组胺药贝波司汀和苯海拉明后大脑组胺H1受体占有率。
Br J Clin Pharmacol. 2008 Jun;65(6):811-21. doi: 10.1111/j.1365-2125.2008.03143.x. Epub 2008 Apr 11.
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Brain structures and mechanisms involved in the control of cortical activation and wakefulness, with emphasis on the posterior hypothalamus and histaminergic neurons.参与控制皮层激活和觉醒的脑结构与机制，重点关注下丘脑后部和组胺能神经元。
Sleep Med Rev. 2000 Oct;4(5):471-503. doi: 10.1053/smrv.2000.0116.
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