儿童和成人呼吸道标本中的默克尔细胞多瘤病毒DNA
Merkel cell polyomavirus DNA in respiratory specimens from children and adults.
作者信息
Bialasiewicz Seweryn, Lambert Stephen B, Whiley David M, Nissen Michael D, Sloots Theo P
机构信息
Research Section, Queensland Paediatric Infectious Diseases Laboratory, Sir Albert Sakzewski Virus Research Centre, Brisbane, Queensland, Australia.
出版信息
Emerg Infect Dis. 2009 Mar;15(3):492-4. doi: 10.3201/eid1503.081067.
Abstract
Merkel cell polyomavirus (MCPyV) DNA was detected in 7 (1.3%) of 526 respiratory tract samples from patients in Australia with upper or lower respiratory tract symptoms. Partial T antigen and major capsid protein sequences of MCPyV identified in respiratory secretions showed high homology (99%-100%) to those found in Merkel cell carcinoma.
摘要
在澳大利亚有上呼吸道或下呼吸道症状患者的526份呼吸道样本中，7份（1.3%）检测到默克尔细胞多瘤病毒（MCPyV）DNA。在呼吸道分泌物中鉴定出的MCPyV的部分T抗原和主要衣壳蛋白序列与在默克尔细胞癌中发现的序列具有高度同源性（99%-100%）。
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