Division of Infectious Diseases, Emory University School of Medicine, 550 Peachtree Street NE, Atlanta, GA 30308, USA.
Curr Infect Dis Rep. 2009 Mar;11(2):157-62. doi: 10.1007/s11908-009-0023-5.
Syphilis and HIV infections frequently occur simultaneously because they affect the same risk groups. The declining incidence of syphilis during the 1990s reversed beginning in 2001, with most of the new cases occurring in men who have sex with men. This group is at highest risk of having or acquiring HIV infection. The clinical presentation of syphilis may be altered in persons with HIV infection and the response to therapy may be affected by immunosuppression. Syphilis may also subtly affect HIV infection, at least transiently. This article reviews the epidemiology, clinical manifestations, and treatment of syphilis in the setting of HIV infection.
梅毒和 HIV 感染经常同时发生，因为它们影响的是相同的高危人群。梅毒的发病率在 20 世纪 90 年代下降后，从 2001 年开始再次上升，大多数新发病例出现在男男性行为者中。这一群体感染 HIV 的风险最高。HIV 感染者的梅毒临床表现可能会发生改变，而免疫抑制可能会影响治疗反应。梅毒也可能会对 HIV 感染产生微妙的影响，至少是短暂的影响。本文回顾了 HIV 感染者中梅毒的流行病学、临床表现和治疗。
