Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
J Am Acad Dermatol. 2020 Jan;82(1):1-14. doi: 10.1016/j.jaad.2019.02.073. Epub 2019 Apr 12.
Syphilis is caused by infection with the spirochetal bacterium Treponema pallidum subsp. pallidum. It was first recognized in the late 15th century. Since 2000, the incidence of sexually acquired syphilis has increased substantially in the developed world, with men who have sex with men and persons living with HIV infection disproportionately affected. Clinical manifestations of syphilis are protean and often include mucocutaneous manifestations. The first article in this continuing medical education series reviews historical aspects, microbiology, epidemiology, and clinical manifestations of sexually acquired syphilis.
梅毒是由苍白密螺旋体亚种苍白密螺旋体引起的感染。它于 15 世纪末首次被发现。自 2000 年以来，发达国家的性传播梅毒发病率大幅上升，受影响最大的是男男性行为者和 HIV 感染者。梅毒的临床表现多种多样，常包括黏膜皮肤表现。本继续医学教育系列的第一篇文章综述了性传播梅毒的历史方面、微生物学、流行病学和临床表现。
