RNA结构的动态图景。

The dynamic landscapes of RNA architecture.

作者信息

Cruz José Almeida, Westhof Eric

机构信息

Architecture et Réactivité de l'ARN, Université de Strasbourg, Institut de Biologie Moléculaire et Cellulaire du CNRS, 67084 Strasbourg, France.

出版信息

Cell. 2009 Feb 20;136(4):604-9. doi: 10.1016/j.cell.2009.02.003.

DOI:10.1016/j.cell.2009.02.003

PMID:19239882

Abstract

A wealth of information on RNA folding and ribonucleoprotein assembly has emerged from analyses of structures and from the use of innovative biophysical tools. Although integrating data obtained from static structures with dynamic measurements presents major challenges, such efforts are opening new vistas on the RNA folding landscape.

摘要

通过对结构的分析以及使用创新的生物物理工具，已经涌现出了大量关于RNA折叠和核糖核蛋白组装的信息。尽管将从静态结构获得的数据与动态测量数据整合起来面临重大挑战，但这些努力正在为RNA折叠领域开辟新的前景。