植物微小RNA的起源、生物发生及活性

Origin, biogenesis, and activity of plant microRNAs.

作者信息

Voinnet Olivier

机构信息

Institut de Biologie Moléculaire des Plantes, CNRS UPR2357-Université de Strasbourg, 67084 Strasbourg, France.

出版信息

Cell. 2009 Feb 20;136(4):669-87. doi: 10.1016/j.cell.2009.01.046.

DOI:10.1016/j.cell.2009.01.046

PMID:19239888

Abstract

MicroRNAs (miRNAs) are key posttranscriptional regulators of eukaryotic gene expression. Plants use highly conserved as well as more recently evolved, species-specific miRNAs to control a vast array of biological processes. This Review discusses current advances in our understanding of the origin, biogenesis, and mode of action of plant miRNAs and draws comparisons with their metazoan counterparts.

摘要

微小RNA（miRNA）是真核生物基因表达的关键转录后调节因子。植物利用高度保守以及最近进化出的物种特异性miRNA来控制大量生物过程。本综述讨论了我们在理解植物miRNA的起源、生物合成和作用模式方面的当前进展，并与后生动物中的对应物进行了比较。