Venancio Roberta de Abreu, Alencar Francisco Guedes Pereira, Zamperini Camila
Marquette University School of Dentistry TMD and Orofacial Pain, P.O. Box 1881 Milwaukee, WI 53201-1881, USA.
Cranio. 2009 Jan;27(1):46-53. doi: 10.1179/crn.2009.008.
Trigger point injections with different solutions have been studied mainly with regard to the management of myofascial pain (MFP) patient management. However, few studies have analyzed their effect in a chronic headache population with associated MFP. The purpose of this study was to assess if trigger point injections using botulinum toxin, lidocaine, and dry-needling injections for the management of local pain and associated headache management. Forty-five (45) myofascial pain patients with headaches that could be reproduced by activating at least one trigger point, were randomly assigned into one of the three groups: G1, dry-needling, G2, 0.25% lidocaine, at 0.25% and G3 botulinum toxin and were assessed during a 12 week period. Levels of pain intensity, frequency and duration, local postinjection sensitivity, obtainment time and duration of relief, and the use of rescue medication were evaluated. Statistically, all the groups showed favorable results for the evaluated requisites (p < or = 0.05), except for the use of rescue medication and local post injection sensitivity (G3 showed better results). Considering its reduced cost, lidocaine could be adopted as a substance of choice, and botulinum toxin should be reserved for refractory cases, in which the expected effects could not be achieved, and the use of a more expensive therapy would be mandatory.
针对不同溶液的触发点注射,主要是围绕肌筋膜疼痛(MFP)患者的管理进行研究的。然而,很少有研究分析其在伴有MFP的慢性头痛人群中的效果。本研究的目的是评估使用肉毒杆菌毒素、利多卡因进行触发点注射以及干针注射在治疗局部疼痛和相关头痛方面的效果。45名因激活至少一个触发点而引发头痛的肌筋膜疼痛患者,被随机分为三组之一:G1组为干针注射,G2组为0.25%利多卡因注射,G3组为肉毒杆菌毒素注射,并在12周内进行评估。评估了疼痛强度、频率和持续时间、注射后局部敏感性、缓解的获得时间和持续时间以及急救药物的使用情况。从统计学角度来看,除了急救药物的使用和注射后局部敏感性(G3组结果更好)外,所有组在评估指标上均显示出良好的结果(p≤0.05)。考虑到成本较低,利多卡因可作为首选药物,而肉毒杆菌毒素应保留用于难治性病例,即无法达到预期效果且必须使用更昂贵治疗方法的情况。